The focus of Daniel Hoffman’s research program is to better understand the relationship between poor growth in childhood and the development of chronic diseases in adulthood. To accomplish this, Hoffman directs or collaborates on research projects in Brazil and Mexico to better understand how poor growth early in life influences metabolism and body composition later in life as potential risk factors for chronic diseases. In addition, Hoffman is a co-principal investigator of a project in Kenya and Zambia to evaluate the impact of increases in intake of African indigenous vegetables on dietary diversity and health in rural households.